Hmmmm....I don't really play blues, so I'm not sure how helpful this will be....but it seems to me that blues players use pretty moderate settings....I'd set your Bass at about 12:00, your Middle at about 2:00, and your treble at about 3:00, with your reverb up around 4:00, and if you have a "gain" knob, keep that at a moderate setting as well, probably somewhere between 9:00 and 12:00.
Like I said, I don't really play blues, and I haven't heard your amp, but these settings should at least get you in the ballpark and give you something to work with.
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