This is a rhythm lick for a standard I-IV-V blues progression, using a chromatic trick that's nice for playing smooth blues background rhythm. It is a shorter version of the full I-IV-V progression, but all the important bits are there.
Note that some bass lines are palm muted. Also, sliding around 6th intervals is a neat blue strick, try to use it in your own playing.
Focus is on the minor pentatonic scale, but with an added major 6th interval of the dorian mode, and moved chromatically (following the E blues note scales on the bass) to the left by two frets for each chord.
I used Amplitube 3 software, tubescreamer and Mesa Boogie MKII emulations. The guitar is a Fender Stratocaster, neck single pickup.